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Depression in Women

Is depression common in women?

Yes. According to the National Institute of Mental Health (NIMH), more than 17 million people in the United States -- 1 in 10 adults -- experience depression each year, and nearly two thirds do not get the help they need. Women are disproportionately affected by depression, experiencing it at roughly twice the rate of men. Research continues to explore how women are affected by depression, but there are some common symptoms.

Women Are at Greater Risk for Depression than Men

Major depression and dysthymia affect twice as many women as men. This two-to-one ratio exists regardless of racial and ethnic background or economic status. The same ratio has been reported in eleven other countries all over the world. Men and women have about the same rate of bipolar disorder (manic depression), though its course in women typically has more depressive and fewer manic episodes. Also, a greater number of women have the rapid cycling form of bipolar disorder, which may be more resistant to standard treatments.

A variety of factors unique to women's lives are suspected to play a role in developing depression. Research is focused on understanding these, including: reproductive, hormonal, genetic or other biological factors; abuse and oppression; interpersonal factors; and certain psychological and personality characteristics. And yet, the specific causes of depression in women remain unclear; many women exposed to these factors do not develop depression. What is clear is that regardless of the contributing factors, depression is a highly treatable illness and that the types of treatment discussed later in this brochure are effective for a majority of women.

What are the symptoms of depression in women?

About 20% of women have depression at least once. If you're depressed, you may have some of these symptoms:

  • Feeling sad, having the "blues" or crying a lot
  • Losing interest or pleasure in your usual activities (including sex)
  • Feeling guilty, hopeless or worthless
  • Thinking about death or suicide
  • Sleeping too much, or not being able to go to sleep or stay asleep
  • Losing your appetite and losing weight (or eating too much and gaining weight)
  • Feeling very tired or slowed down
  • Having trouble paying attention and making decisions
  • Having aches and pains that don't get better with treatment

What causes depression in women?

If some brain chemicals are too low, the brain's nerve cells work slower. This causes depression. Stressful life events, especially the death of a loved one, a divorce or moving (such as leaving home to go to work or to college), may also cause depression.

Women with premenstrual syndrome (PMS) are more likely to get depression. It's more common a week before a period and in the weeks after giving birth.

The Many Dimensions of Depression in Women

Investigators are focusing on the following areas in their study of depression in women:

The issues of adolescence

Studies show that the higher incidence of depression in females begins in adolescence, when roles and expectations change dramatically. The stresses of adolescence include forming an identity, confronting sexuality, separating from parents, and making decisions for the first time, along with other physical, intellectual, and hormonal changes. These stresses are generally different for boys and girls, and may be associated more often with depression in females.

Adulthood: relationships and work roles

It is known that stress in general can contribute to depression in persons biologically vulnerable to the illness. Some have theorized that higher incidence of depression in women is not due to greater vulnerability, but to the particular stresses that many women face. These stresses include major responsibilities at home and work, single parenthood, and caring for children and aging parents, and are areas currently under study. How these factors may uniquely effect women is not yet fully understood.

Reproductive events

Women's reproductive events include the menstrual cycle, pregnancy, the postpregnancy period, infertility, menopause, and sometimes, the decision not to have children. These events bring fluctuations in mood that for some women include depression. Researchers have confirmed that hormones have an effect on the brain chemistry that controls emotions and mood; a specific biological mechanism explaining hormonal involvement is not known, however.

Many women experience certain behavioral and physical changes associated with phases of their menstrual cycles. In some women, these changes are severe, occur regularly, and include depressed feelings, irritability, and other emotional and physical changes. Called premenstrual syndrome, its relation to depressive disorders is not yet understood. Some have questioned whether it is, in fact, a disorder. Further research will no doubt add to our understanding of this long-ignored condition.

Postpartum depressions

can range from transient "blues" following childbirth to severe, incapacitating, psychotic depressions. Studies suggest that women who experience depression after childbirth very often have had prior depressive episodes. However, for most women, postpartum depressions are transient, with no adverse consequences.

Pregnancy (if it is desired) seldom contributes to depression, and having an abortion does not appear to lead to a higher incidence of depression. Women with infertility problems may be subject to extreme anxiety or sadness, though it is unclear if this contributes to a higher rate of depressive illness. In addition, young motherhood may be a time of heightened risk for depression, due to the stress and demands it imposes.

Personality and psychology

Studies indicate that individuals with certain characteristics-- pessimistic thinking, low self-esteem, a sense of having little control over life events, and proneness to excessive worrying-- are more likely to develop depression. These attributes may heighten the effect of stressful events or interfere with taking action to cope with them. Some experts have suggested that the traditional upbringing of girls might foster these traits and that may be a factor in the higher rate of depression.

Others have suggested that women are not more vulnerable to depression than men, but simply express or label their symptoms differently. Women may be more likely to admit feelings of depression, brood about their feelings, or seek professional assistance. Men, on the other hand, may be socially conditioned to deny such feelings or to bury them in alcohol, as reflected in the higher rates of alcoholism in men. Current research may provide some answers about which of these theories is correct.

Victimization

Studies show that women molested as children are more likely to have clinical depression at some time in their lives than those with no such history. In addition, several studies show a higher incidence of depression among women who were raped as adults. Since far more women than men were sexually abused as children, these findings are relevant. Women who experience other commonly occurring forms of abuse, such as physical abuse and sexual harassment on the job, also may experience higher rates of depression. Abuse may lead to depression by fostering low self-esteem, a sense of helplessness, self-blame, and social isolation. At present, more research is needed to understand whether victimization is connected specifically to depression.

Poverty

Women and children represent seventy-five percent of the U.S. population considered poor. Some researchers are therefore exploring the possibility that poverty is one of the "pathways to depression." Low economic status brings with it many stresses, including isolation, uncertainty, frequent negative events, and poor access to helpful resources. Sadness and low morale are more common among persons with low incomes and those lacking social supports. But research has not yet established whether depressive illnesses are more prevalent among those facing environmental stressors such as these. One very large study has shown that these illnesses tend to equally effect the poor and the rich.

Depression in later adulthood

Once, depression at menopause was considered a unique illness known as "involutional melancholia." Research has shown, however, that depressive illnesses are no different, and no more likely to occur, at menopause than at other ages. In fact, the women most vulnerable to change-of-life depression are those with a history of past depressive episodes. An old theory, the "empty nest syndrome", stated that when children leave home, women may experience a profound loss of purpose and identity that leads to depression. However, studies show no increase in depressive illness among women at this stage of life.

As with younger age groups, more elderly women than men suffer from depressive illness. Similarly, for all age groups, being unmarried (which includes widowhood) is also a risk factor for depression. Despite this, depression should not be dismissed as a normal consequence of the physical, social and economic problems of later life. In fact, studies show that most older people feel satisfied with their lives.

About 800,000 persons are widowed each year, most of them are older, female, and experience varying degrees of depressive symptomatology. Most do not need formal treatment, but those who are moderately or severely sad appear to benefit from self-help groups or various psychosocial treatments. Remarkably, a third of widows/widowers meet criteria for major depressive episode in the first month after the death, and half of these remain clinically depressed 1 year later. These depressions respond to standard antidepressant medications, although there is relatively little research on when to start medications or how medications should be combined with psychosocial treatments.

How is depression in women treated?

Counseling alone may help if your depression isn't too bad. It's important to take good care of yourself, to exercise and to eat healthy foods.

If you have depression, your doctor can prescribe a medicine called an antidepressant. Medicine alone or medicine with counseling can help most women who have depression.

It's OK to take birth control pills or hormone replacement therapy at the same time as depression medicines. Taking hormones may even help some depressed women feel better.

If you get pregnant while you're taking a medicine for depression, tell your doctor right away. Your doctor will know if your medicine is safe to take. If you're planning to get pregnant, talk to your doctor about your medicines before you try to get pregnant.

Almost all medicines for depression would pass into your breast milk. Ask your doctor before you start breast feeding.

What should I do if I forget to take a dose of my antidepressant?

If 3 hours have passed, skip the dose. Otherwise, go ahead and take it. If you miss a dose, don't take 2 doses the next time.

What are the side effects of antidepressants?

If you're taking a tricyclic antidepressant, you may have a dry mouth, constipation, blurred vision, a "spacy" feeling, bladder problems, tiredness, sleepiness, dizziness, shaky hands, fast heartbeat or weight gain.

If you're taking a selective serotonin reuptake inhibitor (SSRI), you may have nausea, vomiting, diarrhea, nervousness, sleepiness or trouble sleeping, or problems with sex (inability to have an orgasm).

If a side effect of your antidepressant bothers you, talk to your doctor about it.
How will I know if my medicine is helping my depression?

You'll sleep better. Your appetite will improve, and you will have more energy. You'll have a better feeling about the future. You'll feel less sad, and it will be easier to make decisions. Be patient--it may take about 3 weeks before you start to feel better.

How long will I need to take the medicine?

If this is the first time you've been depressed, you'll probably take the medicine for about 6 months. If this is the second time you've been depressed, you'll probably take the medicine for about 1 year. However, if this is the third or fourth time you've been depressed, you may need to take the medicine for years.

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