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Imipramine for Depression: Drug Information, Side Effects and Precautions

Imipramine is the generic name for the depression medicine Tofranil. It is a tricyclic medication with properties similar to Doxepin, amitriptyline, and others.

It usually is not used to treat manic depression (bipolar disorder) because it could lead to or aggravate a manic episode. Those who have manic depression are usually advised by a mental health doctor to take something different.

Imipramine has also been used to treat chronic bed wetting in small children. You would have to consult a physician to find out what other uses are for this medication. Also, you need a prescription in order to receive Imipramine (Tofranil).

How Imipramine Works

This medication helps prevent e-absorption of noradrenalin and serotonin into nerve cells. As a result, it helps elevate the user’s mood. If you are prescribed this medication you can ask your doctor for more information.

Recommended Daily Dosage

It is important for you to see a mental health professional or medical doctor before you decide to take Imipramine. They can help you determine what exact dosage of this medication will work best for you. You can take this medication with or without food, according to your doctor’s instructions.

Precautions to Take

Imipramine should not be taken with any other antidepressant, especially MAO inhibitors. You need to inform your doctor or pharmacist of any other prescription or non-prescription medications you are taking-even vitamins.

In addition, it is important that you always be honest with your doctor about how you are doing before, during, after being prescribed Imipramine. Serious complications-even death-could result if you are not honest with your doctor.
This medication cannot be combined with quite a few other medicines, and is not recommended for use if you have certain kinds of medical conditions, such as those with a thyroid condition. You need to be careful to get the right opinion regarding this drug.

In addition, you need to know that consuming alcoholic beverages while consuming this medication could increase side effects. Therefore, these should be avoided.

Furthermore, those who take Imipramine should not drive a vehicle, operate heavy (or dangerous) machinery, or climb to high elevations for several days. You should wait to see how Imipramine will affect you before performing any of the above, or any other heavy-duty tasks.

If you are allergic to Imipramine you should call your doctor immediately. Your local mental health center will be able to find you a different medication.

Many other precautions need to be considered when taking this medication. You can ask your doctor about it.

In Case of Overdose

If you accidentally overdose and it negatively affects your body, you will need to seek medical help immediately. For less urgent cases regarding overdose you will want to contact your local poison control center.

Side effects of Imipramine

Usually all medications, including Imipramine, come with extensive information regarding side effects. It is important to consult your doctor before you take this medication.

The side affects that people experience the most while taking Imipramine often are the ones that are the least harmful to most people. Lists of some of the least serious and most serious side affects of this medication are listed below:

Some of the less serious side effects of this medication include the following:

  • Dry mouth or dry eyes
  • Drowsiness, weakness, nausea
  • Dizziness, sweating, or fatigue
  • Mild tremor, agitation, headache
  • Constipation
  • Loss of weight or appetite

Some of the more serious, but less common side effects include on or more of the following:

  • Allergic reaction (Swelling of your lips, tongue, or face; difficulty breathing, closing of your throat, hives, etc.) or rash
  • Seizures
  • Fast or irregular heartbeat
  • High blood pressure
  • High fever, muscle stiffness, or muscle weakness
  • Difficulty urinating

Most of the above-mentioned more severe side effects as well as others not listed on this page do not happen very often. Likewise, side effects that are most common are also ones that are the least fatal or the least harmful. If uncomfortable, painful, or harmful side effects persist, you will want to consult your psychiatrist right away.

What to Do if You Experience Side Effects

If you notice some unusual uncomfortable activity within your body while you take Imipramine, contact your doctor. Your doctor can carefully analyze the situation and help determine whether or not you should continue taking this medication.

How to Store your medication

You need to seal up your Imipramine tight in the container that it came in. Along with that, you need to store it at room temperature, away from excess heat or light. Also, remember to throw away any outdated unused medication and keep hidden from children.

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Disclaimer: This site is for educational purposes only. The information provided should not be used for diagnosing or treating a health problem or disease. If you have, or suspect you have a health problem, you should consult your health care provider.

This page is about: Imipramine, Depression Medicine, Tricyclic Medication, Imipramine Side Effects